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Symbol
Name
ID
Alox5
arachidonate 5-lipoxygenase
MGI:87999
Phenotype annotations related to immune system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Lymphadenopathy
Hepatosplenomegaly
Peritoneal abscess
Asthma
Disease(s) Associated with ALOX5
asthma
pancreatic cancer

Mouse Phenotypes
immune system phenotype
impaired neutrophil chemotaxis
small spleen
abnormal neutrophil physiology
impaired neutrophil recruitment
abnormal immune system physiology
decreased susceptibility to type I hypersensitivity reaction
decreased susceptibility to experimental autoimmune uveoretinitis
abnormal inflammatory response
decreased acute inflammation
decreased inflammatory response
Availability Mouse Genotype
Alox5tm1Bhk/Alox5tm1Bhk
Alox5tm1Fun/Alox5tm1Fun *

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory